|
gptkbp:instanceOf
|
gptkb:protein
gptkb:enzyme
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
Immunodeficiency-centromeric instability-facial anomalies syndrome
ICF syndrome type 1
|
|
gptkbp:biologicalProcess
|
DNA methylation
epigenetic regulation of gene expression
DNA (cytosine-5)-methyltransferase activity
|
|
gptkbp:EC_number
|
2.1.1.220
|
|
gptkbp:encodedBy
|
DNMT3B gene
|
|
gptkbp:Entrez_Gene_ID
|
GC20P051234
|
|
gptkbp:function
|
de novo DNA methylation
|
|
gptkbp:GO_term
|
GO:0003886
|
|
gptkbp:HGNC_ID
|
2977
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
DNA methyltransferase 3B
|
|
gptkbp:length
|
853 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:20q11.2
|
|
gptkbp:location
|
gptkb:nucleus
|
|
gptkbp:molecularWeight
|
97 kDa
|
|
gptkbp:OMIM
|
602900
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:proteinFamily
|
DNA methyltransferase family
|
|
gptkbp:RefSeq
|
NP_006575.2
|
|
gptkbp:relatedTo
|
gptkb:DNMT1
gptkb:DNMT3A
|
|
gptkbp:structure
|
contains methyltransferase domain
contains PWWP domain
contains ADD domain
|
|
gptkbp:substrate
|
cytosine in CpG dinucleotides
|
|
gptkbp:UniProtID
|
Q9UBC3
|
|
gptkbp:bfsParent
|
gptkb:DNMT3B
gptkb:decitabine
|
|
gptkbp:bfsLayer
|
8
|