|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:ICF
DNA MTase HsaIIIB
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:cancer
Immunodeficiency-centromeric instability-facial anomalies syndrome (ICF syndrome)
|
|
gptkbp:component
|
gptkb:nucleus
|
|
gptkbp:discoveredIn
|
1998
|
|
gptkbp:encodes
|
gptkb:DNA_methyltransferase_3B
|
|
gptkbp:Entrez_Gene_ID
|
1789
ENSG00000167286
|
|
gptkbp:expressedIn
|
various tissues
|
|
gptkbp:fullName
|
DNA (cytosine-5)-methyltransferase 3 beta
|
|
gptkbp:function
|
epigenetic regulation
DNA (cytosine-5)-methyltransferase activity
de novo DNA methylation
|
|
gptkbp:GOProcess
|
DNA methylation
|
|
gptkbp:HGNC_ID
|
2974
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
DNMT3B
|
|
gptkbp:locatedOnChromosome
|
gptkb:20q11.21
chromosome 20
|
|
gptkbp:mutationAssociatedWith
|
genomic instability
abnormal DNA methylation patterns
|
|
gptkbp:OMIM
|
602900
|
|
gptkbp:orthologInMouse
|
Dnmt3b
|
|
gptkbp:proteinFamily
|
DNA methyltransferase family
|
|
gptkbp:UniProtID
|
Q9UBC3
|
|
gptkbp:bfsParent
|
gptkb:DNA_methyltransferase
gptkb:SETDB1
|
|
gptkbp:bfsLayer
|
7
|