Statements (32)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:DEAD-box_helicases
|
| gptkbp:contains |
conserved helicase core domain
|
| gptkbp:database |
gptkb:InterPro:_IPR014001
gptkb:Pfam:_PF00270 |
| gptkbp:example |
gptkb:DDX5
gptkb:DDX6 gptkb:Dbp5 gptkb:eIF4A DDX3X |
| gptkbp:firstDescribed |
1988
|
| gptkbp:foundIn |
prokaryotes
eukaryotes |
| gptkbp:function |
RNA helicase activity
|
| gptkbp:GO_term |
GO:0004386 (helicase activity)
|
| https://www.w3.org/2000/01/rdf-schema#label |
DEAD box proteins
|
| gptkbp:involvedIn |
splicing
translation initiation RNA transport RNA metabolism ribosome assembly RNA decay |
| gptkbp:motif |
Asp-Glu-Ala-Asp (DEAD)
|
| gptkbp:mutationAssociatedWith |
gptkb:cancer
neurological disorders |
| gptkbp:numberOfMembers |
over 30 in humans
|
| gptkbp:powerSource |
gptkb:ATP
|
| gptkbp:relatedTo |
DEAH box proteins
RNA helicases |
| gptkbp:structure |
two RecA-like domains
|
| gptkbp:bfsParent |
gptkb:DEAD_box_protein_family
|
| gptkbp:bfsLayer |
8
|