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gptkbp:instanceOf
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gptkb:protein
gptkb:gene
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gptkbp:alternativeName
|
CD209
Dendritic Cell-Specific Intercellular adhesion molecule-3-Grabbing Non-integrin
|
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gptkbp:binds
|
gptkb:Cytomegalovirus
gptkb:HIV-1_gp120
gptkb:Dengue_virus
gptkb:ICAM-2
gptkb:ICAM-3
Ebola virus glycoprotein
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gptkbp:biologicalProcess
|
carbohydrate binding
mannose binding
|
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gptkbp:cellularComponent
|
gptkb:plasma_membrane
|
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gptkbp:discoveredBy
|
Yvette van Kooyk
|
|
gptkbp:discoveredIn
|
2000
|
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gptkbp:encodedBy
|
CD209 gene
|
|
gptkbp:Entrez_Gene_ID
|
30835
|
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gptkbp:expressedIn
|
dendritic cells
|
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gptkbp:foundIn
|
gptkb:Homo_sapiens
|
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gptkbp:function
|
cell adhesion
pathogen recognition
|
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gptkbp:glycosylation
|
N-linked glycosylation
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
DC-SIGN (CD209)
|
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gptkbp:involvedIn
|
immune response
antigen presentation
pathogen entry
|
|
gptkbp:locatedOn
|
gptkb:chromosome_19
|
|
gptkbp:OMIM
|
604672
|
|
gptkbp:orthologIn
|
mouse CD209a
|
|
gptkbp:pathway
|
innate immune system
lectin pathway of complement activation
|
|
gptkbp:regulates
|
downregulated by IFN-gamma
upregulated by IL-4
|
|
gptkbp:significance
|
tuberculosis
HIV infection
dengue fever
|
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gptkbp:species
|
primates
|
|
gptkbp:structure
|
transmembrane protein
|
|
gptkbp:subcellularLocation
|
cell surface
endocytic vesicle
|
|
gptkbp:type
|
gptkb:C-type_lectin_receptor
|
|
gptkbp:UniProtID
|
Q9NNX6
|
|
gptkbp:bfsParent
|
gptkb:CD299
|
|
gptkbp:bfsLayer
|
8
|