Statements (51)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
pattern recognition receptor |
| gptkbp:activatedBy |
adaptive immune response
innate immune response |
| gptkbp:alternativeName |
gptkb:CLR
C-type lectin-like receptor |
| gptkbp:associatedWith |
gptkb:cancer
infectious diseases autoimmune diseases |
| gptkbp:binds |
carbohydrates
|
| gptkbp:domain |
C-type lectin domain
|
| gptkbp:encodedBy |
various genes
|
| gptkbp:expressedIn |
immune cells
|
| gptkbp:foundIn |
gptkb:fish
birds amphibians mammals reptiles |
| gptkbp:function |
immune response modulation
pathogen recognition |
| https://www.w3.org/2000/01/rdf-schema#label |
C-type lectin receptor
|
| gptkbp:includes |
gptkb:DC-SIGN
Dectin-1 Dectin-2 Mannose receptor Mincle |
| gptkbp:involvedIn |
gptkb:allergy
inflammation autoimmunity phagocytosis cytokine production antigen presentation tolerance induction |
| gptkbp:pathway |
gptkb:NF-κB_pathway
CARD9 pathway Syk pathway |
| gptkbp:recognizedBy |
parasites
viruses fungal pathogens bacterial pathogens |
| gptkbp:regulates |
inflammatory response
tissue homeostasis immune cell activation |
| gptkbp:requires |
calcium
|
| gptkbp:structure |
extracellular domain
cytoplasmic tail transmembrane protein |
| gptkbp:bfsParent |
gptkb:Pattern_Recognition_Receptor
gptkb:Langerin gptkb:Langerin_(CD207) |
| gptkbp:bfsLayer |
7
|