DB00981

GPTKB entity

Statements (74)
Predicate Object
gptkbp:instanceOf gptkb:drug
gptkbp:approvalYear 1994
gptkbp:approvedBy gptkb:FDA
gptkbp:ATCCode A10BA02
gptkbp:bioavailability 50-60%
gptkbp:brand gptkb:Diabex
gptkb:Metfogamma
gptkb:Metforal
gptkb:Metformin_Hydrochloride
gptkb:Riomet
gptkb:Siofor
gptkb:Dianben
gptkb:Metformax
gptkb:Obimet
gptkb:Fortamet
gptkb:Glucophage
gptkb:Glumetza
Metformin Teva
Glifage
Metformin Accord
Metformin Mylan
Metformin Sandoz
Metformin AL
Metformin AbZ
Metformin Aristo
Metformin Basics
Metformin Fair-Med
Metformin Glenmark
Metformin Heumann
Metformin Hexal
Metformin Hormosan
Metformin Neuraxpharm
Metformin Puren
Metformin Ratiopharm
Metformin STADA
Metformin Stada
Metformin TAD
Metformin Winthrop
Metformin Zentiva
Metformin beta
Metformin dura
Metformin-ratiopharm
gptkbp:CASNumber 657-24-9
gptkbp:contraindication metabolic acidosis
hypersensitivity
renal impairment
gptkbp:excretion renal
gptkbp:halfLife 4-8.7 hours
gptkbp:hasMolecularFormula C4H11N5
https://www.w3.org/2000/01/rdf-schema#label DB00981
gptkbp:indication gptkb:polycystic_ovary_syndrome
gptkb:type_2_diabetes_mellitus
gptkbp:legalStatus prescription only
gptkbp:mechanismOfAction decreases hepatic glucose production
increases insulin sensitivity
gptkbp:metabolism not metabolized
gptkbp:molecularWeight 129.164
gptkbp:name gptkb:Metformin
gptkbp:pregnancyCategory B (US)
gptkbp:proteinBinding negligible
gptkbp:PubChem_CID gptkb:DB00981
gptkbp:routeOfAdministration oral
gptkbp:sideEffect nausea
diarrhea
gastrointestinal upset
lactic acidosis
gptkbp:synonym gptkb:Glucophage
gptkb:Metformina
gptkb:Metformine
gptkb:Metforminum
gptkbp:target gptkb:AMP-activated_protein_kinase
gptkb:mitochondrial_respiratory_chain_complex_I
gptkbp:bfsParent gptkb:Physostigmine
gptkbp:bfsLayer 6