Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
|
| gptkbp:administeredBy |
oral
|
| gptkbp:approvalYear |
1957
|
| gptkbp:approvedBy |
gptkb:France
gptkb:FDA |
| gptkbp:ATCCode |
A10BA02
|
| gptkbp:availableOn |
gptkb:tablet
extended-release tablet |
| gptkbp:brand |
gptkb:metformin
|
| gptkbp:chemicalFormula |
C4H11N5
|
| gptkbp:combines |
gptkb:insulin
gptkb:DPP-4_inhibitors gptkb:GLP-1_agonists sulfonylureas |
| gptkbp:compatibleWith |
type 1 diabetes
|
| gptkbp:contraindication |
gptkb:liver_disease
alcoholism renal impairment |
| gptkbp:discoveredIn |
1950s
|
| gptkbp:eliminationHalfLife |
4-8.7 hours
|
| gptkbp:excretion |
kidneys
|
| gptkbp:genericAvailable |
yes
|
| https://www.w3.org/2000/01/rdf-schema#label |
Glucophage
|
| gptkbp:manufacturer |
gptkb:Merck_Sante
|
| gptkbp:mechanismOfAction |
decreases hepatic glucose production
increases insulin sensitivity |
| gptkbp:pregnancyCategory |
B (US)
|
| gptkbp:prescriptionStatus |
prescription only
|
| gptkbp:sideEffect |
gastrointestinal upset
lactic acidosis |
| gptkbp:usedFor |
gptkb:type_2_diabetes
|
| gptkbp:bfsParent |
gptkb:默克
|
| gptkbp:bfsLayer |
5
|