|
gptkbp:instance_of
|
gptkb:drug
|
|
gptkbp:bfsLayer
|
4
|
|
gptkbp:bfsParent
|
gptkb:Metformin
|
|
gptkbp:activities
|
increases insulin sensitivity
decreases hepatic glucose production
|
|
gptkbp:brand
|
gptkb:Fortamet
|
|
gptkbp:class
|
biguanide
|
|
gptkbp:clinical_trial
|
NC T00012345
NC T00067890
NC T00123456
|
|
gptkbp:contraindication
|
gptkb:healthcare_organization
heart failure
liver disease
|
|
gptkbp:dosage_form
|
oral
|
|
gptkbp:duration
|
long-term
|
|
gptkbp:effective_date
|
2001-04-01
|
|
gptkbp:form
|
extended-release tablet
|
|
gptkbp:frequency
|
once daily
twice daily
|
|
gptkbp:has_ability
|
500 mg
1000 mg
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Fortamet
|
|
gptkbp:ingredients
|
gptkb:metformin
|
|
gptkbp:interacts_with
|
gptkb:physicist
gptkb:cimetidine
diuretics
contraceptives
|
|
gptkbp:is_involved_in
|
adults
children over 10
|
|
gptkbp:is_monitored_by
|
liver function tests
blood glucose levels
kidney function tests
Hb A1c levels
|
|
gptkbp:is_used_for
|
type 2 diabetes
|
|
gptkbp:manager
|
oral
|
|
gptkbp:manufacturer
|
gptkb:Bristol-Myers_Squibb
|
|
gptkbp:packaging
|
gptkb:beer
|
|
gptkbp:products
|
gptkb:Metformin
gptkb:Glucophage
Glumetza
|
|
gptkbp:requires
|
prescription only
|
|
gptkbp:scholarships
|
avoid alcohol
take with food
monitor kidney function
|
|
gptkbp:shelf_life
|
check label
|
|
gptkbp:side_effect
|
nausea
stomach upset
diarrhea
lactic acidosis
hypoglycemia
vitamin B12 deficiency
|
|
gptkbp:storage
|
room temperature
away from moisture
away from heat
|