|
gptkbp:instanceOf
|
gptkb:brand
gptkb:drug
|
|
gptkbp:activeIngredient
|
metformin hydrochloride
|
|
gptkbp:approvalYear
|
2005
|
|
gptkbp:ATCCode
|
A10BA02
|
|
gptkbp:contraindication
|
metabolic acidosis
renal impairment
|
|
gptkbp:drugClass
|
gptkb:biguanide
|
|
gptkbp:eliminatedIn
|
renal
|
|
gptkbp:form
|
500 mg
extended-release tablet
1000 mg
|
|
gptkbp:genericAvailable
|
yes
|
|
gptkbp:halfLife
|
6.2 hours
|
|
gptkbp:indication
|
gptkb:type_2_diabetes_mellitus
|
|
gptkbp:legalStatus
|
Rx-only
|
|
gptkbp:manufacturer
|
gptkb:Bausch_Health
|
|
gptkbp:marketedIn
|
gptkb:United_States
|
|
gptkbp:mechanismOfAction
|
decreases hepatic glucose production
increases insulin sensitivity
decreases intestinal absorption of glucose
|
|
gptkbp:NDCCode
|
62037-0541
62037-0542
|
|
gptkbp:patentLitigation
|
subject to patent litigation
|
|
gptkbp:pregnancyCategory
|
B
|
|
gptkbp:prescriptionStatus
|
prescription only
|
|
gptkbp:regulates
|
approved
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
nausea
diarrhea
abdominal discomfort
gastrointestinal upset
lactic acidosis
|
|
gptkbp:bfsParent
|
gptkb:Valeant_Pharmaceuticals
gptkb:DB00740
|
|
gptkbp:bfsLayer
|
6
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Glumetza
|