Statements (36)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:drug
|
| gptkbp:approvalYear |
2001
|
| gptkbp:approvedBy |
gptkb:FDA
|
| gptkbp:ATCCode |
L01XE01
|
| gptkbp:brand |
gptkb:Gleevec
gptkb:Glivec |
| gptkbp:CASNumber |
152459-95-5
|
| gptkbp:developedBy |
gptkb:Novartis
|
| gptkbp:genericName |
gptkb:imatinib
|
| gptkbp:hasMolecularFormula |
C29H31N7O
|
| gptkbp:hasPatentExpiry |
2015 (US)
|
| gptkbp:hasSMILES |
CC1=CC=CC=C1NC(=O)C2=CC=CC=C2N3C=NC=N3
|
| gptkbp:hasUNII |
8CIP0O835V
|
| https://www.w3.org/2000/01/rdf-schema#label |
D07714
|
| gptkbp:isApprovedDrug |
true
|
| gptkbp:mechanismOfAction |
gptkb:receptor_tyrosine_kinase
|
| gptkbp:molecularWeight |
493.6
|
| gptkbp:pregnancyCategory |
D (US)
|
| gptkbp:PubChem_CID |
gptkb:D07714
gptkb:CHEMBL941 gptkb:DB00619 5291 |
| gptkbp:routeOfAdministration |
oral
|
| gptkbp:sideEffect |
nausea
edema rash muscle cramps |
| gptkbp:target |
gptkb:BCR-ABL
gptkb:PDGFR gptkb:c-KIT |
| gptkbp:usedFor |
gptkb:gastrointestinal_stromal_tumor
gptkb:chronic_myeloid_leukemia |
| gptkbp:bfsParent |
gptkb:Clomipramine
gptkb:DB01235 gptkb:clomipramine |
| gptkbp:bfsLayer |
7
|