|
gptkbp:instanceOf
|
gptkb:enzyme
|
|
gptkbp:alternativeName
|
gptkb:CYP3A5
cytochrome P450, family 3, subfamily A, polypeptide 5
|
|
gptkbp:associatedWith
|
gptkb:kidney_disease
hypertension
drug response variability
|
|
gptkbp:EC_number
|
1.14.14.1
|
|
gptkbp:encodedBy
|
CYP3A5 gene
|
|
gptkbp:expressedIn
|
gptkb:kidney
liver
intestine
|
|
gptkbp:foundIn
|
gptkb:Homo_sapiens
|
|
gptkbp:function
|
monooxygenase activity
drug metabolism
xenobiotic metabolism
|
|
gptkbp:gene
|
gptkb:CYP3A5
|
|
gptkbp:hasPolymorphism
|
CYP3A5*1
CYP3A5*3
|
|
gptkbp:HGNC_ID
|
2597
|
|
gptkbp:inducedBy
|
gptkb:rifampicin
gptkb:phenytoin
gptkb:carbamazepine
|
|
gptkbp:inhibitedBy
|
gptkb:clarithromycin
gptkb:ketoconazole
itraconazole
|
|
gptkbp:locatedIn
|
gptkb:endoplasmic_reticulum
|
|
gptkbp:locatedOnChromosome
|
chromosome 7q22.1
|
|
gptkbp:member
|
gptkb:cytochrome_P450_superfamily
|
|
gptkbp:molecularWeight
|
57 kDa
|
|
gptkbp:OMIM
|
605340
|
|
gptkbp:orthologInMouse
|
Cyp3a11
Cyp3a1
|
|
gptkbp:PDB
|
5VEU
|
|
gptkbp:RefSeq
|
NM_000777
|
|
gptkbp:substrate
|
gptkb:nifedipine
gptkb:tacrolimus
gptkb:midazolam
testosterone
|
|
gptkbp:UniProtID
|
P20815
|
|
gptkbp:bfsParent
|
gptkb:CYP3A5
|
|
gptkbp:bfsLayer
|
8
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Cytochrome P450 3A5
|