|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:advantage
|
Cas9 (in some applications)
|
|
gptkbp:alsoKnownAs
|
gptkb:Cas12-family_protein
|
|
gptkbp:application
|
diagnostics
base editing
gene knockout
gene insertion
|
|
gptkbp:cleavage
|
staggered cut
sticky ends
|
|
gptkbp:compatibleWith
|
gptkb:tracrRNA
PAM on both DNA strands
|
|
gptkbp:discoveredBy
|
gptkb:Feng_Zhang
|
|
gptkbp:firstDescribed
|
2015
|
|
gptkbp:foundIn
|
gptkb:Bacteria
archaea
|
|
gptkbp:function
|
gptkb:endonuclease
genome editing
|
|
gptkbp:mechanismOfAction
|
interference with foreign DNA
|
|
gptkbp:memberOf
|
gptkb:CRISPR-associated_proteins
|
|
gptkbp:PAMSequence
|
TTTV
|
|
gptkbp:recognizedBy
|
gptkb:crRNA
|
|
gptkbp:relatedTo
|
gptkb:Cas9
|
|
gptkbp:requires
|
gptkb:crRNA
|
|
gptkbp:structure
|
single RNA-guided endonuclease
|
|
gptkbp:subspecies
|
gptkb:Cas12a
gptkb:Cas12b
gptkb:Cas12c
gptkb:Cas12d
gptkb:Cas12e
gptkb:Cas12f
|
|
gptkbp:target
|
gptkb:gene
|
|
gptkbp:usedFor
|
animal genome editing
plant genome editing
multiplex genome editing
bacterial genome editing
|
|
gptkbp:usedIn
|
gptkb:DETECTR_diagnostic_platform
gptkb:SHERLOCK_diagnostic_platform
genome engineering
|
|
gptkbp:bfsParent
|
gptkb:Cas12l
|
|
gptkbp:bfsLayer
|
7
|
|
http://www.w3.org/2000/01/rdf-schema#label
|
Cpf1-family protein
|