Cluster of Differentiation 22
GPTKB entity
Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:CD22
|
| gptkbp:cellSurfaceMarker |
gptkb:B_cells
|
| gptkbp:compatibleWith |
gptkb:T_cells
plasma cells |
| gptkbp:domain |
immunoglobulin-like domains
|
| gptkbp:encodedBy |
gptkb:CD22_gene
|
| gptkbp:Entrez_Gene_ID |
933
|
| gptkbp:expressedIn |
mature B cells
|
| gptkbp:foundIn |
gptkb:B_cells
humans |
| gptkbp:function |
inhibition of B cell activation
regulation of B cell receptor signaling |
| https://www.w3.org/2000/01/rdf-schema#label |
Cluster of Differentiation 22
|
| gptkbp:interactsWith |
sialic acid-containing glycoproteins
|
| gptkbp:location |
chromosome 19q13.1
|
| gptkbp:molecularWeight |
140 kDa
|
| gptkbp:OMIM |
107266
|
| gptkbp:role |
autoimmune diseases
B cell lymphomas |
| gptkbp:structure |
type I transmembrane protein
|
| gptkbp:target |
gptkb:epratuzumab
gptkb:inotuzumab_ozogamicin monoclonal antibodies |
| gptkbp:UniProtID |
gptkb:P20273
|
| gptkbp:usedAs |
therapeutic target in B cell malignancies
|
| gptkbp:bfsParent |
gptkb:CD22
gptkb:CD-22 |
| gptkbp:bfsLayer |
7
|