Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alternativeName |
BL-CAM
Leukocyte surface antigen CD22 SIGLEC-2 |
| gptkbp:associatedWith |
gptkb:B-cell_lymphomas
autoimmune diseases |
| gptkbp:discoveredBy |
multiple research groups in the 1980s
|
| gptkbp:encodes |
CD22 protein
|
| gptkbp:Entrez_Gene_ID |
gptkb:ENSG00000012124
933 |
| gptkbp:expressedIn |
gptkb:B_lymphocytes
|
| gptkbp:function |
inhibition of B-cell activation
regulation of B-cell receptor signaling |
| gptkbp:HGNC_ID |
HGNC:1642
|
| https://www.w3.org/2000/01/rdf-schema#label |
CD22 gene
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_19
19q13.1 |
| gptkbp:mutationAssociatedWith |
can lead to immunodeficiency
|
| gptkbp:OMIM |
107266
|
| gptkbp:orthologInMouse |
Cd22
|
| gptkbp:product |
cell surface receptor
|
| gptkbp:proteinFamily |
SIGLEC family
|
| gptkbp:species |
gptkb:Homo_sapiens
|
| gptkbp:target |
monoclonal antibody therapies
|
| gptkbp:UniProtID |
gptkb:P20273
|
| gptkbp:bfsParent |
gptkb:CD22
gptkb:CD-22 |
| gptkbp:bfsLayer |
7
|