Cluster of Differentiation 19
GPTKB entity
Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:cell_surface_marker |
| gptkbp:abbreviation |
gptkb:CD19
|
| gptkbp:compatibleWith |
gptkb:NK_cells
gptkb:T_cells myeloid cells |
| gptkbp:discoveredIn |
1980s
|
| gptkbp:encodedBy |
gptkb:CD19_gene
|
| gptkbp:expressedIn |
gptkb:lymphoid_tissue
|
| gptkbp:foundIn |
gptkb:B_cells
|
| gptkbp:function |
B cell activation
B cell development B cell signaling |
| gptkbp:locatedOnChromosome |
gptkb:chromosome_16
|
| gptkbp:molecularWeight |
~95 kDa
|
| gptkbp:OMIM |
107265
|
| gptkbp:significance |
diagnosis of B cell malignancies
monitoring of leukemia |
| gptkbp:structure |
transmembrane glycoprotein
|
| gptkbp:target |
gptkb:gene_therapy
monoclonal antibodies |
| gptkbp:UniProtID |
gptkb:P15391
|
| gptkbp:usedAs |
B cell marker
|
| gptkbp:usedIn |
immunophenotyping
flow cytometry |
| gptkbp:bfsParent |
gptkb:B-lymphocyte_antigen_CD19
|
| gptkbp:bfsLayer |
8
|
| http://www.w3.org/2000/01/rdf-schema#label |
Cluster of Differentiation 19
|