Cluster of Differentiation 19
GPTKB entity
Statements (28)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
cell surface marker |
gptkbp:abbreviation |
gptkb:CD19
|
gptkbp:compatibleWith |
gptkb:NK_cells
gptkb:T_cells myeloid cells |
gptkbp:discoveredIn |
1980s
|
gptkbp:encodedBy |
gptkb:CD19_gene
|
gptkbp:expressedIn |
lymphoid tissue
|
gptkbp:foundIn |
gptkb:B_cells
|
gptkbp:function |
B cell activation
B cell development B cell signaling |
https://www.w3.org/2000/01/rdf-schema#label |
Cluster of Differentiation 19
|
gptkbp:locatedOnChromosome |
gptkb:chromosome_16
|
gptkbp:molecularWeight |
~95 kDa
|
gptkbp:OMIM |
107265
|
gptkbp:significance |
diagnosis of B cell malignancies
monitoring of leukemia |
gptkbp:structure |
transmembrane glycoprotein
|
gptkbp:target |
gene therapy
monoclonal antibodies |
gptkbp:UniProtID |
gptkb:P15391
|
gptkbp:usedAs |
B cell marker
|
gptkbp:usedIn |
immunophenotyping
flow cytometry |
gptkbp:bfsParent |
gptkb:B-lymphocyte_antigen_CD19
|
gptkbp:bfsLayer |
7
|