Statements (44)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
gptkb:G_proteins
|
| gptkbp:alternativeName |
gptkb:Secretin_receptor_family
|
| gptkbp:associatedWith |
gptkb:cancer
gptkb:depression gptkb:bone gptkb:diabetes obesity |
| gptkbp:contains |
seven transmembrane domains
|
| gptkbp:encodedBy |
various genes
|
| gptkbp:evolvesFrom |
early metazoans
|
| gptkbp:foundIn |
gptkb:metazoans
|
| gptkbp:function |
signal transduction
hormone binding neurotransmitter binding |
| https://www.w3.org/2000/01/rdf-schema#label |
Class B GPCR
|
| gptkbp:includes |
gptkb:glucagon_receptor
gptkb:secretin_receptor calcitonin receptor parathyroid hormone receptor vasoactive intestinal peptide receptor corticotropin-releasing hormone receptor growth hormone-releasing hormone receptor pituitary adenylate cyclase-activating polypeptide receptor glucagon-like peptide receptor glucose-dependent insulinotropic polypeptide receptor |
| gptkbp:InterPro |
gptkb:IPR000832
|
| gptkbp:involvedIn |
bone metabolism
stress response metabolic regulation calcium homeostasis endocrine signaling |
| gptkbp:ligand |
peptide hormones
neuropeptides |
| gptkbp:MembranousLocation |
gptkb:cell_membrane
|
| gptkbp:numberOfGenes |
15
|
| gptkbp:proteinFamily |
gptkb:PF00002
|
| gptkbp:structure |
disulfide bonds
conserved cysteine residues large extracellular N-terminus |
| gptkbp:subclassOf |
gptkb:G_protein-coupled_receptor
|
| gptkbp:target |
pharmaceutical drugs
|
| gptkbp:bfsParent |
gptkb:secretin_receptor
|
| gptkbp:bfsLayer |
6
|