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gptkbp:instanceOf
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gptkb:protein
gptkb:CRISPR-Cas_system
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gptkbp:alternativeName
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C2c2
Cpf1 (incorrect, sometimes confused)
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gptkbp:discoveredBy
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gptkb:Feng_Zhang
gptkb:Jonathan_Gootenberg
gptkb:Omar_Abudayyeh
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gptkbp:doesNotTarget
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gptkb:gene
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gptkbp:domain
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HEPN domain
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gptkbp:foundIn
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gptkb:Bacteria
archaea
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gptkbp:function
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gptkb:CRISPR-Cas_system
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gptkbp:hasActivity
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RNA cleavage
collateral RNA degradation
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https://www.w3.org/2000/01/rdf-schema#label
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Cas13 protein
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gptkbp:mechanismOfAction
|
collateral cleavage of RNA
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gptkbp:partOf
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CRISPR-Cas adaptive immune system
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gptkbp:PDB
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gptkb:5XWP
gptkb:6DTD
6I1K
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gptkbp:requires
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gptkb:CRISPR_RNA_(crRNA)
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gptkbp:studiedIn
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gptkb:Bacteria
gptkb:Leptotrichia_shahii
gptkb:Ruminococcus_flavefaciens
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gptkbp:subspecies
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gptkb:Cas13a
gptkb:Cas13b
gptkb:Cas13c
gptkb:Cas13d
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gptkbp:target
|
single-stranded RNA
|
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gptkbp:usedFor
|
COVID-19 diagnostics
programmable RNA targeting
viral detection
|
|
gptkbp:usedIn
|
gptkb:biotechnology
gptkb:SHERLOCK_diagnostic_platform
synthetic biology
diagnostics
functional genomics
RNA base editing
RNA editing
gene knockdown
high-throughput screening
live-cell RNA imaging
transcriptome engineering
antiviral defense
RNA virus interference
mammalian cell RNA knockdown
plant gene silencing
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gptkbp:bfsParent
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gptkb:CRISPR-Cas13
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gptkbp:bfsLayer
|
6
|