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gptkbp:instanceOf
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RNA-targeting CRISPR system
genome editing technology
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gptkbp:alternativeName
|
gptkb:Type_VI_CRISPR_system
C2c2
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gptkbp:component
|
prokaryotic adaptive immune system
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gptkbp:contains
|
gptkb:Cas13_protein
gptkb:guide_RNA
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gptkbp:discoveredBy
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gptkb:Feng_Zhang
gptkb:Jonathan_Gootenberg
gptkb:Omar_Abudayyeh
|
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gptkbp:discoveredIn
|
2016
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gptkbp:doesNotTarget
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gptkb:gene
|
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gptkbp:family
|
gptkb:Class_2_Type_VI_CRISPR_system
|
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gptkbp:firstPublished
|
gptkb:Cell_journal
2016
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|
https://www.w3.org/2000/01/rdf-schema#label
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CRISPR-Cas13
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gptkbp:mechanismOfAction
|
collateral cleavage of RNA
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gptkbp:patent
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gptkb:Broad_Institute
|
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gptkbp:relatedTo
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gptkb:CRISPR-Cas12
gptkb:CRISPR-Cas9
|
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gptkbp:subspecies
|
gptkb:Cas13a
gptkb:Cas13b
gptkb:Cas13c
gptkb:Cas13d
|
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gptkbp:target
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gptkb:gene
|
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gptkbp:usedFor
|
gptkb:SHERLOCK_diagnostic_platform
molecular diagnostics
diagnostics
biotechnology research
functional genomics
RNA base editing
RNA editing
RNA knockdown
RNA splicing modulation
RNA virus detection
antiviral applications
high-throughput screening
live-cell RNA imaging
programmable RNA targeting
therapeutic development
transcriptome engineering
|
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gptkbp:usedIn
|
COVID-19 diagnostics
gene expression regulation
viral detection
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gptkbp:bfsParent
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gptkb:Mammoth_Biosciences
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gptkbp:bfsLayer
|
5
|