Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:CRISPR-Cas_system |
| gptkbp:affiliatedWith |
gptkb:Type_VI_CRISPR_system
Class 2 CRISPR system |
| gptkbp:alsoKnownAs |
C2c2
|
| gptkbp:cleavage |
gptkb:gene
|
| gptkbp:collateralActivity |
non-specific RNA cleavage after target recognition
|
| gptkbp:determines |
gptkb:cryo-EM
|
| gptkbp:discoveredBy |
gptkb:Feng_Zhang
|
| gptkbp:firstDescribed |
2015
|
| gptkbp:foundIn |
gptkb:Leptotrichia_shahii
|
| gptkbp:function |
gptkb:CRISPR-Cas_system
|
| gptkbp:gene |
cas13a
|
| gptkbp:hasCollateralActivity |
true
|
| https://www.w3.org/2000/01/rdf-schema#label |
Cas13a
|
| gptkbp:PDB |
5XWY
|
| gptkbp:recognizedBy |
single-stranded RNA
|
| gptkbp:regulates |
phage defense in bacteria
|
| gptkbp:requires |
gptkb:crRNA
|
| gptkbp:usedFor |
viral diagnostics
SARS-CoV-2 detection RNA detection |
| gptkbp:usedIn |
gptkb:SHERLOCK_diagnostic_platform
CRISPR gene editing diagnostics RNA knockdown |
| gptkbp:bfsParent |
gptkb:CRISPR-Cas13
|
| gptkbp:bfsLayer |
6
|