Statements (24)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:gene |
| gptkbp:alternativeName |
cytochrome P450 51
sterol 14-demethylase |
| gptkbp:encodes |
lanosterol 14-alpha demethylase
|
| gptkbp:enzymeCommissionNumber |
EC 1.14.14.154
|
| gptkbp:familyMember |
gptkb:cytochrome_P450
|
| gptkbp:foundIn |
animals
fungi plants |
| gptkbp:function |
catalyzes demethylation of lanosterol
|
| gptkbp:gene |
gptkb:CYP51
|
| https://www.w3.org/2000/01/rdf-schema#label |
CYP51
|
| gptkbp:inhibitionLeadsTo |
disruption of cell membrane synthesis
|
| gptkbp:involvedIn |
sterol biosynthesis
|
| gptkbp:orthologIn |
gptkb:yeast
humans plants |
| gptkbp:requires |
ergosterol biosynthesis in fungi
|
| gptkbp:structureType |
heme-thiolate protein
|
| gptkbp:target |
azole antifungal drugs
|
| gptkbp:bfsParent |
gptkb:cytochrome_P450_enzymes
gptkb:cytochrome_P450_superfamily |
| gptkbp:bfsLayer |
6
|