Statements (35)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:Cpf1_family
|
| gptkbp:application |
biosensing
diagnostics gene editing |
| gptkbp:discoveredBy |
gptkb:Feng_Zhang
gptkb:Jennifer_Doudna |
| gptkbp:distinctFrom |
produces staggered DNA cuts
recognizes T-rich PAM requires shorter guide RNA |
| gptkbp:firstDescribed |
2015
|
| gptkbp:foundIn |
gptkb:Bacteria
archaea |
| gptkbp:function |
genome editing
DNA cleavage |
| https://www.w3.org/2000/01/rdf-schema#label |
CRISPR-Cas12 family
|
| gptkbp:mechanismOfAction |
single RNA-guided endonuclease
|
| gptkbp:member |
gptkb:Cas12a
gptkb:Cas12b gptkb:Cas12c gptkb:Cas12d gptkb:Cas12e gptkb:Cas12f gptkb:Cas12g gptkb:Cas12h |
| gptkbp:PAM_sequence |
TTTV
|
| gptkbp:partOf |
gptkb:CRISPR-Cas_system
|
| gptkbp:relatedTo |
gptkb:CRISPR-Cas9
|
| gptkbp:target |
double-stranded DNA
|
| gptkbp:usedIn |
gptkb:DETECTR_diagnostic_assay
gptkb:SHERLOCK_diagnostic_assay |
| gptkbp:bfsParent |
gptkb:Cas12c
gptkb:Cas12o gptkb:Cas12s |
| gptkbp:bfsLayer |
7
|