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gptkbp:instanceOf
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gptkb:CRISPR-Cas_system
genome editing technology
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gptkbp:alsoKnownAs
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gptkb:Cpf1
|
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gptkbp:cleavage
|
single-stranded DNA
double-stranded DNA
|
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gptkbp:compatibleWith
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gptkb:tracrRNA
|
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gptkbp:component
|
CRISPR adaptive immune system
|
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gptkbp:discoveredBy
|
gptkb:Emmanuelle_Charpentier
gptkb:Feng_Zhang
gptkb:Jennifer_Doudna
|
|
gptkbp:firstDescribed
|
2015
|
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gptkbp:foundIn
|
gptkb:Bacteria
archaea
|
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gptkbp:function
|
genome editing
nucleic acid detection
targeted DNA cleavage
|
|
gptkbp:hasCollateralActivity
|
single-stranded DNA cleavage
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CRISPR-Cas12
|
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gptkbp:patent
|
gptkb:Broad_Institute
gptkb:University_of_California
|
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gptkbp:recognizedBy
|
PAM sequence
|
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gptkbp:relatedTo
|
gptkb:CRISPR-Cas13
gptkb:CRISPR-Cas9
|
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gptkbp:requires
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gptkb:crRNA
|
|
gptkbp:structure
|
single RNA-guided endonuclease
|
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gptkbp:subspecies
|
gptkb:Cas12a
gptkb:Cas12b
gptkb:Cas12c
gptkb:Cas12d
gptkb:Cas12e
gptkb:Cas12f
gptkb:Cas12g
gptkb:Cas12h
gptkb:Cas12i
gptkb:Cas12j
gptkb:Cas12k
gptkb:Cas12l
gptkb:Cas12m
gptkb:Cas12n
gptkb:Cas12o
gptkb:Cas12p
gptkb:Cas12q
gptkb:Cas12r
gptkb:Cas12s
gptkb:Cas12t
gptkb:Cas12u
gptkb:Cas12v
gptkb:Cas12w
gptkb:Cas12x
gptkb:Cas12y
gptkb:Cas12z
|
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gptkbp:targetRecognition
|
T-rich PAM sequence
|
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gptkbp:usedFor
|
gptkb:DETECTR_diagnostic_platform
gptkb:SHERLOCK_diagnostic_platform
|
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gptkbp:usedIn
|
gptkb:biotechnology
diagnostics
gene therapy
|
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gptkbp:bfsParent
|
gptkb:Mammoth_Biosciences
gptkb:CRISPR
|
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gptkbp:bfsLayer
|
5
|