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gptkbp:instanceOf
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gptkb:protein
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gptkbp:alsoKnownAs
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gptkb:Complement_receptor_type_2
gptkb:CD21
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gptkbp:associatedWith
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gptkb:systemic_lupus_erythematosus
autoimmune diseases
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gptkbp:biologicalProcess
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gptkb:B_cell_receptor_signaling_pathway
complement activation
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gptkbp:cellularComponent
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gptkb:plasma_membrane
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gptkbp:encodedBy
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gptkb:CR2_gene
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gptkbp:expressedIn
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gptkb:B_cells
gptkb:follicular_dendritic_cells
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gptkbp:foundIn
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gptkb:Homo_sapiens
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gptkbp:function
|
binds complement component C3d
serves as receptor for Epstein-Barr virus
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|
https://www.w3.org/2000/01/rdf-schema#label
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CR2 protein
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gptkbp:interactsWith
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gptkb:iC3b
gptkb:C3dg
gptkb:Epstein-Barr_virus_gp350/220
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gptkbp:locatedOnChromosome
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gptkb:chromosome_1q32
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gptkbp:molecularWeight
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145 kDa
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gptkbp:OMIM
|
120650
|
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gptkbp:roleInImmuneSystem
|
enhances B cell activation
involved in immune complex trapping
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gptkbp:structure
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contains 15-16 short consensus repeats (SCRs)
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gptkbp:UniProtID
|
P20023
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gptkbp:bfsParent
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gptkb:CR2_domain
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gptkbp:bfsLayer
|
6
|