Complement receptor type 2

URI: https://gptkb.org/entity/Complement_receptor_type_2
GPTKB entity
Statements (31)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alsoKnownAs gptkb:CR2
gptkb:CD21
gptkbp:alternativeSplicing yes
gptkbp:antigen gptkb:CD21
gptkbp:associatedWith gptkb:systemic_lupus_erythematosus
autoimmune diseases
gptkbp:discoveredIn 1970s
gptkbp:encodedBy gptkb:CR2_gene
gptkbp:expressedIn gptkb:B_cells
gptkb:follicular_dendritic_cells
gptkbp:extracellularDomains 15-16 short consensus repeats (SCRs)
gptkbp:foundIn humans
other mammals
gptkbp:function binds complement component C3d
binds Epstein-Barr virus (EBV)
gptkbp:HGNC_ID 2334
https://www.w3.org/2000/01/rdf-schema#label Complement receptor type 2
gptkbp:interactsWith gptkb:CD19
gptkb:CD81
gptkbp:locatedOn chromosome 1 (human)
gptkbp:membraneSpanningDomains 1
gptkbp:molecularWeight 145 kDa
gptkbp:OMIM 120650
gptkbp:partOf gptkb:B_cell_co-receptor_complex
gptkbp:role B cell activation
immune response regulation
gptkbp:structure transmembrane glycoprotein
gptkbp:UniProtID P20023
gptkbp:bfsParent gptkb:CR2_protein
gptkbp:bfsLayer 7