|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alias
|
gptkb:BGP
BGP1
CD66a
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:discoveredBy
|
Shively JE et al.
|
|
gptkbp:Entrez_Gene_ID
|
634
ENSG00000105388
|
|
gptkbp:expressedIn
|
gptkb:leukocytes
endothelial cells
epithelial cells
|
|
gptkbp:family
|
CEA family
|
|
gptkbp:fullName
|
Carcinoembryonic antigen-related cell adhesion molecule 1
|
|
gptkbp:function
|
cell adhesion
immune response regulation
inhibition of T cell activation
|
|
gptkbp:GO_term
|
gptkb:GO:0006955_(immune_response)
GO:0007155 (cell adhesion)
|
|
gptkbp:HGNC_ID
|
HGNC:1814
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CEACAM1
|
|
gptkbp:interactsWith
|
gptkb:CEACAM5
TIM-3
CEACAM6
|
|
gptkbp:locatedOnChromosome
|
19q13.2
|
|
gptkbp:location
|
gptkb:cell_membrane
|
|
gptkbp:molecularWeight
|
~85 kDa
|
|
gptkbp:numberOfExons
|
9
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
mouse Ceacam1
rat Ceacam1
|
|
gptkbp:PDB
|
2GK2
2QSQ
|
|
gptkbp:postTranslationalModification
|
phosphorylation
glycosylation
|
|
gptkbp:regulates
|
apoptosis
angiogenesis
insulin clearance
|
|
gptkbp:role
|
gptkb:cancer
gptkb:diabetes
autoimmune diseases
inflammatory diseases
|
|
gptkbp:signalPeptide
|
yes
|
|
gptkbp:structure
|
gptkb:immunoglobulin_superfamily
|
|
gptkbp:subcellularLocation
|
gptkb:plasma_membrane
extracellular region
|
|
gptkbp:symbol
|
gptkb:CEACAM1
|
|
gptkbp:transmembraneDomains
|
yes
|
|
gptkbp:UniProtID
|
P13688
|
|
gptkbp:bfsParent
|
gptkb:CEACAM5
|
|
gptkbp:bfsLayer
|
7
|