|
gptkbp:instanceOf
|
gptkb:protein
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:CEA
Carcinoembryonic antigen
CD66e
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:antibodyTarget
|
yes
|
|
gptkbp:associatedWith
|
gptkb:cancer
colorectal cancer
pancreatic cancer
|
|
gptkbp:cellularComponent
|
gptkb:cell_membrane
|
|
gptkbp:discoveredBy
|
gptkb:Phil_Gold
|
|
gptkbp:discoveredIn
|
1965
|
|
gptkbp:downregulatedIn
|
normal adult tissues
|
|
gptkbp:encodes
|
Carcinoembryonic antigen
|
|
gptkbp:Entrez_Gene_ID
|
1048
ENSG00000105388
|
|
gptkbp:expressedIn
|
gastrointestinal tract
urinary tract
fetal development
epithelial cells
respiratory tract
reproductive tract
|
|
gptkbp:function
|
intracellular signaling
cell adhesion
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:glycosylation
|
heavily glycosylated
|
|
gptkbp:GPI-anchored
|
yes
|
|
gptkbp:HGNC_ID
|
HGNC:1817
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CEACAM5
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_19
|
|
gptkbp:memberOf
|
CEA family
|
|
gptkbp:molecularWeight
|
~180 kDa
|
|
gptkbp:NCBI_RefSeq
|
NM_004363
|
|
gptkbp:OMIM
|
114890
|
|
gptkbp:orthologInMouse
|
Ceacam1
|
|
gptkbp:PDB
|
2QSQ
|
|
gptkbp:proteinFamily
|
gptkb:immunoglobulin_superfamily
|
|
gptkbp:relatedTo
|
gptkb:CEACAM1
CEACAM6
|
|
gptkbp:transmembraneDomains
|
no
|
|
gptkbp:UniProtID
|
P06731
|
|
gptkbp:upregulatedBy
|
tumor tissues
|
|
gptkbp:usedAs
|
biomarker
|
|
gptkbp:usedIn
|
cancer diagnosis
cancer prognosis
monitoring cancer therapy
|
|
gptkbp:bfsParent
|
gptkb:carcinoembryonic_antigen
|
|
gptkbp:bfsLayer
|
6
|