Statements (23)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:protein
|
gptkbp:alsoKnownAs |
gptkb:CD45
|
gptkbp:compatibleWith |
non-hematopoietic cells
|
gptkbp:discoveredIn |
1970s
|
gptkbp:encodedBy |
gptkb:PTPRC_gene
|
gptkbp:expressedIn |
all differentiated hematopoietic cells except erythrocytes and plasma cells
|
gptkbp:foundIn |
gptkb:leukocytes
|
gptkbp:function |
regulation of T- and B-cell antigen receptor signaling
|
gptkbp:hasIsoform |
gptkb:CD45RA
gptkb:CD45RB gptkb:CD45RO |
https://www.w3.org/2000/01/rdf-schema#label |
leukocyte common antigen
|
gptkbp:location |
gptkb:cell_membrane
|
gptkbp:marking |
hematopoietic cells
|
gptkbp:molecularWeight |
180-220 kDa
|
gptkbp:OMIM |
151460
|
gptkbp:significance |
diagnosis of lymphomas
|
gptkbp:structure |
transmembrane protein tyrosine phosphatase
|
gptkbp:target |
monoclonal antibodies
|
gptkbp:UniProtID |
P08575
|
gptkbp:usedIn |
immunohistochemistry
|
gptkbp:bfsParent |
gptkb:CD45
|
gptkbp:bfsLayer |
7
|