CD154

GPTKB entity

Statements (24)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:alsoKnownAs gptkb:CD40_ligand
gptkb:CD40L
gptkbp:binds gptkb:CD40
gptkbp:encodedBy CD40LG gene
gptkbp:expressedIn activated T cells
gptkbp:foundIn humans
other mammals
gptkbp:function costimulatory molecule for T cell activation
https://www.w3.org/2000/01/rdf-schema#label CD154
gptkbp:involves gptkb:hyper-IgM_syndrome
atherosclerosis
autoimmune diseases
gptkbp:locatedOnChromosome Xq26
gptkbp:memberOf tumor necrosis factor (TNF) superfamily
gptkbp:role immune response
B cell activation
immunoglobulin class switching
macrophage activation
dendritic cell maturation
gptkbp:UniProtID P29965
gptkbp:bfsParent gptkb:tumor_necrosis_factor_ligand_superfamily_member_3
gptkb:CD40_ligand
gptkbp:bfsLayer 8