|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alias
|
gptkb:CD3-epsilon
gptkb:IMD18
gptkb:T3E
gptkb:CD3E
|
|
gptkbp:alternativeSplicing
|
yes
|
|
gptkbp:associatedWith
|
gptkb:immunodeficiency_18
gptkb:immunodeficiency
|
|
gptkbp:component
|
gptkb:T_cell_receptor_complex
gptkb:T-cell_receptor-CD3_complex
|
|
gptkbp:discoveredBy
|
multiple researchers
|
|
gptkbp:encodes
|
gptkb:CD3-epsilon_polypeptide
|
|
gptkbp:Entrez_Gene_ID
|
916
ENSG00000198851
|
|
gptkbp:expressedIn
|
gptkb:T_cells
|
|
gptkbp:firstDescribed
|
1980s
|
|
gptkbp:function
|
signal transduction
protein binding
T-cell activation
transmembrane signaling receptor activity
|
|
gptkbp:GOProcess
|
gptkb:T_cell_receptor_signaling_pathway
adaptive immune response
|
|
gptkbp:hasTranscriptVariant
|
multiple
|
|
gptkbp:HGNC_ID
|
HGNC:1675
|
|
gptkbp:interactsWith
|
gptkb:CD247_protein
gptkb:CD3D_protein
gptkb:CD3G_protein
gptkb:TCR_alpha/beta_complex
gptkb:TCR_gamma/delta_complex
|
|
gptkbp:length
|
207 amino acids
|
|
gptkbp:locatedOnChromosome
|
chromosome 11
11q23.3
|
|
gptkbp:molecularWeight
|
23 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:immunodeficiency
|
|
gptkbp:OMIM
|
186830
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologInMouse
|
gptkb:Cd3e
|
|
gptkbp:product
|
gptkb:CD3-epsilon_chain
|
|
gptkbp:referenceGenome
|
gptkb:GRCh38
|
|
gptkbp:subcellularLocation
|
gptkb:cell_membrane
|
|
gptkbp:UniProtID
|
P07766
|
|
gptkbp:bfsParent
|
gptkb:CD3
|
|
gptkbp:bfsLayer
|
6
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CD3E gene
|