|
gptkbp:instanceOf
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gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:CD3e
gptkb:T3E
gptkb:T-cell_surface_glycoprotein_CD3_epsilon_chain
|
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gptkbp:cellSurfaceMarker
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gptkb:CD3
|
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gptkbp:component
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gptkb:T-cell_receptor-CD3_complex
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gptkbp:cytoplasmicDomain
|
contains ITAM motif
|
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gptkbp:encodedBy
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gptkb:CD3E_gene
|
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gptkbp:expressedIn
|
gptkb:thymus
peripheral blood T cells
|
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gptkbp:extracellularDomain
|
immunoglobulin-like domain
|
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gptkbp:foundIn
|
T lymphocyte
|
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gptkbp:function
|
signal transduction
|
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gptkbp:HGNC_ID
|
1675
|
|
gptkbp:interactsWith
|
gptkb:T-cell_receptor_alpha_chain
gptkb:T-cell_receptor_beta_chain
gptkb:CD3-delta_chain
gptkb:CD3-gamma_chain
gptkb:CD3-zeta_chain
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_11q23
|
|
gptkbp:molecularWeight
|
20-25 kDa
|
|
gptkbp:mutationAssociatedWith
|
gptkb:immunodeficiency
|
|
gptkbp:OMIM
|
186830
|
|
gptkbp:postTranslationalModification
|
phosphorylation
|
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gptkbp:requires
|
T-cell development
TCR surface expression
|
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gptkbp:species
|
gptkb:Mus_musculus
gptkb:Homo_sapiens
|
|
gptkbp:structure
|
single-pass type I membrane protein
|
|
gptkbp:UniProtID
|
P07766
|
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gptkbp:bfsParent
|
gptkb:CD3E_gene
|
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gptkbp:bfsLayer
|
7
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CD3-epsilon chain
|