|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:CD3e
gptkb:T3E
gptkb:T-cell_surface_glycoprotein_CD3_epsilon_chain
|
|
gptkbp:cellSurfaceMarker
|
gptkb:CD3
|
|
gptkbp:component
|
gptkb:T-cell_receptor-CD3_complex
|
|
gptkbp:cytoplasmicDomain
|
contains ITAM motif
|
|
gptkbp:encodedBy
|
gptkb:CD3E_gene
|
|
gptkbp:expressedIn
|
gptkb:thymus
peripheral blood T cells
|
|
gptkbp:extracellularDomain
|
immunoglobulin-like domain
|
|
gptkbp:foundIn
|
T lymphocyte
|
|
gptkbp:function
|
signal transduction
|
|
gptkbp:HGNC_ID
|
1675
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CD3-epsilon chain
|
|
gptkbp:interactsWith
|
gptkb:T-cell_receptor_alpha_chain
gptkb:T-cell_receptor_beta_chain
gptkb:CD3-delta_chain
gptkb:CD3-gamma_chain
gptkb:CD3-zeta_chain
|
|
gptkbp:locatedOnChromosome
|
gptkb:chromosome_11q23
|
|
gptkbp:molecularWeight
|
20-25 kDa
|
|
gptkbp:mutationAssociatedWith
|
immunodeficiency
|
|
gptkbp:OMIM
|
186830
|
|
gptkbp:postTranslationalModification
|
phosphorylation
|
|
gptkbp:requires
|
T-cell development
TCR surface expression
|
|
gptkbp:species
|
gptkb:Mus_musculus
gptkb:Homo_sapiens
|
|
gptkbp:structure
|
single-pass type I membrane protein
|
|
gptkbp:UniProtID
|
P07766
|
|
gptkbp:bfsParent
|
gptkb:CD3E_gene
|
|
gptkbp:bfsLayer
|
7
|