Statements (23)
| Predicate | Object | 
|---|---|
| gptkbp:instanceOf | gptkb:protein | 
| gptkbp:compatibleWith | gptkb:HIV-2 | 
| gptkbp:discoveredIn | 1988 | 
| gptkbp:encodedBy | vpu gene | 
| gptkbp:foundIn | gptkb:HIV-1 | 
| gptkbp:function | downregulation of CD4 enhancement of virion release | 
| gptkbp:interactsWith | gptkb:CD4 BST-2 (Tetherin) | 
| gptkbp:length | 81 amino acids | 
| gptkbp:locale | gptkb:endoplasmic_reticulum gptkb:plasma_membrane | 
| gptkbp:locatedOnChromosome | between env and tat genes in HIV-1 genome | 
| gptkbp:molecularWeight | 16 kDa | 
| gptkbp:phosphorylates | serine 52 serine 56 | 
| gptkbp:presentIn | gptkb:HIV-1_group_M | 
| gptkbp:role | immune evasion viral pathogenesis | 
| gptkbp:structure | transmembrane protein | 
| gptkbp:bfsParent | gptkb:CD317 | 
| gptkbp:bfsLayer | 8 | 
| https://www.w3.org/2000/01/rdf-schema#label | Vpu protein of HIV-1 |