Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:compatibleWith |
gptkb:HIV-2
|
| gptkbp:discoveredIn |
1988
|
| gptkbp:encodedBy |
vpu gene
|
| gptkbp:foundIn |
gptkb:HIV-1
|
| gptkbp:function |
downregulation of CD4
enhancement of virion release |
| https://www.w3.org/2000/01/rdf-schema#label |
Vpu protein of HIV-1
|
| gptkbp:interactsWith |
gptkb:CD4
BST-2 (Tetherin) |
| gptkbp:length |
81 amino acids
|
| gptkbp:locale |
gptkb:endoplasmic_reticulum
gptkb:plasma_membrane |
| gptkbp:locatedOnChromosome |
between env and tat genes in HIV-1 genome
|
| gptkbp:molecularWeight |
16 kDa
|
| gptkbp:phosphorylates |
serine 52
serine 56 |
| gptkbp:presentIn |
gptkb:HIV-1_group_M
|
| gptkbp:role |
immune evasion
viral pathogenesis |
| gptkbp:structure |
transmembrane protein
|
| gptkbp:bfsParent |
gptkb:CD317
|
| gptkbp:bfsLayer |
8
|