|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alsoKnownAs
|
gptkb:CD317
gptkb:HM1.24
Tetherin
|
|
gptkbp:associatedWith
|
multiple myeloma
autoimmune diseases
|
|
gptkbp:cellSurfaceMarker
|
yes
|
|
gptkbp:discoveredBy
|
gptkb:Ishikawa_et_al.
|
|
gptkbp:disulfideBond
|
yes
|
|
gptkbp:encodes
|
bone marrow stromal antigen 2
|
|
gptkbp:Entrez_Gene_ID
|
684
ENSG00000130303
|
|
gptkbp:expressedIn
|
gptkb:hepatocytes
monocytes
plasma cells
various cancer cells
|
|
gptkbp:firstDescribed
|
1995
|
|
gptkbp:function
|
involved in innate immune response
inhibits release of enveloped viruses from infected cells
|
|
gptkbp:glycosylation
|
yes
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
BST2
|
|
gptkbp:inhibitedBy
|
Ebola virus release
HIV-1 release
Lassa virus release
|
|
gptkbp:length
|
180 amino acids
|
|
gptkbp:locatedOnChromosome
|
gptkb:19p13.2
|
|
gptkbp:membraneAnchor
|
gptkb:GPI-anchor
|
|
gptkbp:OMIM
|
610593
|
|
gptkbp:orthologInMouse
|
Bst2
|
|
gptkbp:product
|
type II transmembrane protein
|
|
gptkbp:regulates
|
gptkb:interferon-gamma
gptkb:interferon-alpha
gptkb:interleukin-27
|
|
gptkbp:species
|
gptkb:Homo_sapiens
|
|
gptkbp:structure
|
contains coiled-coil domain
contains transmembrane domain
contains cytoplasmic tail
contains extracellular domain
|
|
gptkbp:target
|
HIV-1 Vpu protein
KSHV K5 protein
|
|
gptkbp:UniProtID
|
Q10588
|
|
gptkbp:bfsParent
|
gptkb:CD317
|
|
gptkbp:bfsLayer
|
8
|