Statements (29)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:insulin_receptor
|
| gptkbp:associatedWith |
gptkb:diabetes_mellitus
|
| gptkbp:biologicalProcess |
receptor tyrosine kinase activity
|
| gptkbp:discoveredBy |
gptkb:Ora_Rosen
|
| gptkbp:discoveredIn |
1985
|
| gptkbp:EC_number |
2.7.10.1
|
| gptkbp:expressedIn |
gptkb:skeletal_muscle
liver adipose tissue |
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
mediates insulin signaling
|
| gptkbp:gene |
gptkb:INSR
|
| https://www.w3.org/2000/01/rdf-schema#label |
CD220
|
| gptkbp:interactsWith |
gptkb:SHC1
gptkb:insulin gptkb:IRS1 |
| gptkbp:locatedOnChromosome |
gptkb:19p13.2
|
| gptkbp:location |
gptkb:cell_membrane
|
| gptkbp:mutationAssociatedWith |
insulin resistance
|
| gptkbp:OMIM |
147670
|
| gptkbp:phosphorylates |
tyrosine residues
|
| gptkbp:structure |
heterotetramer
|
| gptkbp:subunit |
alpha subunit
beta subunit |
| gptkbp:UniProtID |
P06213
|
| gptkbp:bfsParent |
gptkb:INSR
gptkb:INSR_gene |
| gptkbp:bfsLayer |
7
|