|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:alternativeName
|
gptkb:CaMKIV
gptkb:CaM_kinase_IV
|
|
gptkbp:component
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:encodedBy
|
CAMK4 gene
|
|
gptkbp:enzymeClassification
|
gptkb:EC_2.7.11.17
|
|
gptkbp:expressedIn
|
gptkb:testis
gptkb:thymus
brain
|
|
gptkbp:fullName
|
Calcium/calmodulin-dependent protein kinase type IV
|
|
gptkbp:function
|
protein serine/threonine kinase activity
serine/threonine-protein kinase
involved in transcriptional regulation
mediates Ca2+/calmodulin-dependent signaling
|
|
gptkbp:gene
|
gptkb:CAMK4
|
|
gptkbp:GOProcess
|
regulation of transcription, DNA-templated
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
CAMK4
|
|
gptkbp:locatedOnChromosome
|
5q22.1
|
|
gptkbp:location
|
gptkb:nucleus
gptkb:cytoplasm
|
|
gptkbp:molecularWeight
|
52 kDa
|
|
gptkbp:mutationAssociatedWith
|
intellectual disability (rare)
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:Mus_musculus
gptkb:Rattus_norvegicus
|
|
gptkbp:pathway
|
gptkb:MAPK_signaling_pathway
gptkb:cAMP_signaling_pathway
calcium signaling pathway
|
|
gptkbp:PDB
|
2W4O
|
|
gptkbp:phosphorylates
|
gptkb:CREB
gptkb:HDAC4
gptkb:SRF
|
|
gptkbp:regulates
|
regulated by phosphorylation
activated by Ca2+/calmodulin
|
|
gptkbp:UniProtID
|
gptkb:Q16566
|
|
gptkbp:bfsParent
|
gptkb:CAMKK1
gptkb:CAMKK2
gptkb:CaMKIV
gptkb:CAMK
gptkb:Ca2+/calmodulin-dependent_protein_kinases
|
|
gptkbp:bfsLayer
|
8
|