Statements (33)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alias |
gptkb:BRCC1
Brca-1 mBrca1 |
| gptkbp:associatedWith |
DNA repair
homologous recombination |
| gptkbp:biologicalProcess |
E3 ubiquitin-protein ligase activity
|
| gptkbp:domain |
gptkb:BRCT_domain
RING finger domain |
| gptkbp:encodes |
BRCA1 protein (mouse)
|
| gptkbp:Entrez_Gene_ID |
12189
|
| gptkbp:expressedIn |
various tissues
|
| gptkbp:foundIn |
gptkb:Mus_musculus
|
| gptkbp:function |
tumor suppressor
|
| https://www.w3.org/2000/01/rdf-schema#label |
Brca1 (Mus musculus)
|
| gptkbp:interactsWith |
gptkb:CtIP
gptkb:BARD1 gptkb:PALB2 gptkb:p53 gptkb:RAD51 |
| gptkbp:involvedIn |
cell cycle checkpoint
genomic stability |
| gptkbp:length |
1863 amino acids
|
| gptkbp:locatedOnChromosome |
chromosome 11
|
| gptkbp:MGI_ID |
MGI:104537
|
| gptkbp:mutationAssociatedWith |
increased cancer susceptibility
|
| gptkbp:OMIM |
113705
|
| gptkbp:orthologIn |
BRCA1 (Homo sapiens)
|
| gptkbp:regulates |
transcription
DNA damage response |
| gptkbp:UniProtID |
Q61166
|
| gptkbp:bfsParent |
gptkb:ENSG00000145675
|
| gptkbp:bfsLayer |
6
|