Bone Morphogenetic Protein 9

URI: https://gptkb.org/entity/Bone_Morphogenetic_Protein_9
GPTKB entity
Statements (33)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:abbreviation gptkb:BMP9
gptkbp:binds gptkb:endoglin
type I and type II serine/threonine kinase receptors
gptkbp:cleavage gptkb:furin
gptkbp:discoveredBy Vukicevic et al.
gptkbp:discoveredIn 1995
gptkbp:Entrez_Gene_ID 2658
gptkbp:expressedIn gptkb:bone
liver
gptkbp:function induces bone and cartilage development
regulates angiogenesis
regulates iron metabolism
gptkbp:gene gptkb:GDF2
gptkbp:locatedOnChromosome gptkb:10q11.22
gptkbp:memberOf gptkb:TGF-beta_superfamily
gptkbp:molecularWeight 12 kDa (mature form)
gptkbp:orthologIn gptkb:mouse
gptkb:right
gptkbp:precursorProtein pro-BMP9
gptkbp:recipient gptkb:ALK1
gptkb:ALK2
BMPR-II
gptkbp:regulates endothelial cell proliferation
hepcidin expression
gptkbp:relatedTo gptkb:hereditary_hemorrhagic_telangiectasia
osteogenesis
liver fibrosis
gptkbp:structure dimer
gptkbp:UniProtID Q9UK05
gptkbp:bfsParent gptkb:BMP9
gptkbp:bfsLayer 7
https://www.w3.org/2000/01/rdf-schema#label Bone Morphogenetic Protein 9