Bone Morphogenetic Protein 9

GPTKB entity

Predicate	Object
gptkbp:instanceOf	gptkb:protein
gptkbp:abbreviation	gptkb:BMP9
gptkbp:binds	gptkb:endoglin type I and type II serine/threonine kinase receptors
gptkbp:cleavage	gptkb:furin
gptkbp:discoveredBy	Vukicevic et al.
gptkbp:discoveredIn	1995
gptkbp:Entrez_Gene_ID	2658
gptkbp:expressedIn	gptkb:bone liver
gptkbp:function	induces bone and cartilage development regulates angiogenesis regulates iron metabolism
gptkbp:gene	gptkb:GDF2
gptkbp:locatedOnChromosome	gptkb:10q11.22
gptkbp:memberOf	gptkb:TGF-beta_superfamily
gptkbp:molecularWeight	12 kDa (mature form)
gptkbp:orthologIn	gptkb:mouse gptkb:right
gptkbp:precursorProtein	pro-BMP9
gptkbp:recipient	gptkb:ALK1 gptkb:ALK2 BMPR-II
gptkbp:regulates	endothelial cell proliferation hepcidin expression
gptkbp:relatedTo	gptkb:hereditary_hemorrhagic_telangiectasia osteogenesis liver fibrosis
gptkbp:structure	dimer
gptkbp:UniProtID	Q9UK05
gptkbp:bfsParent	gptkb:BMP9
gptkbp:bfsLayer	7
http://www.w3.org/2000/01/rdf-schema#label	Bone Morphogenetic Protein 9