Statements (21)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
Activin receptor-like kinase 2
|
| gptkbp:associatedWith |
gptkb:fibrodysplasia_ossificans_progressiva
|
| gptkbp:expressedIn |
various tissues including skeletal muscle and bone
|
| gptkbp:function |
serine/threonine kinase activity
type I receptor for bone morphogenetic proteins (BMPs) |
| gptkbp:gene |
ACVR1
|
| https://www.w3.org/2000/01/rdf-schema#label |
ALK2
|
| gptkbp:interactsWith |
gptkb:SMAD1
gptkb:SMAD5 gptkb:SMAD8 |
| gptkbp:involvedIn |
gptkb:BMP_signaling_pathway
|
| gptkbp:locatedOnChromosome |
2q24.1
|
| gptkbp:location |
gptkb:cell_membrane
|
| gptkbp:molecularWeight |
57 kDa
|
| gptkbp:mutationAssociatedWith |
gain-of-function mutations cause abnormal bone formation
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:phosphorylates |
serine/threonine residues
|
| gptkbp:UniProtID |
Q04771
|
| gptkbp:bfsParent |
gptkb:BMP9
|
| gptkbp:bfsLayer |
7
|