Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alsoKnownAs |
gptkb:CD105
|
| gptkbp:domain |
Orphan domain
Zona pellucida-like domain |
| gptkbp:encodedBy |
gptkb:ENG_gene
|
| gptkbp:expressedIn |
vascular endothelial cells
|
| gptkbp:foundIn |
humans
other mammals |
| gptkbp:function |
co-receptor for transforming growth factor beta (TGF-β)
|
| gptkbp:glycosylation |
yes
|
| gptkbp:hasBiomarker |
tumor angiogenesis
|
| https://www.w3.org/2000/01/rdf-schema#label |
endoglin
|
| gptkbp:interactsWith |
ALK1 receptor
TGF-β receptor complex TGF-β1 TGF-β3 |
| gptkbp:involvedIn |
angiogenesis
|
| gptkbp:locatedOnChromosome |
gptkb:chromosome_9q34.11
|
| gptkbp:location |
cell surface
|
| gptkbp:molecularWeight |
~180 kDa
|
| gptkbp:mutationAssociatedWith |
hereditary hemorrhagic telangiectasia type 1 (HHT1)
|
| gptkbp:OMIM |
131195
|
| gptkbp:structure |
homodimer
|
| gptkbp:transmembraneDomains |
yes
|
| gptkbp:UniProtID |
P17813
|
| gptkbp:usedIn |
cancer research
|
| gptkbp:bfsParent |
gptkb:ENG_gene
|
| gptkbp:bfsLayer |
7
|