|
gptkbp:instanceOf
|
gptkb:protein
|
|
gptkbp:discoveredBy
|
gptkb:Stanley_J._Korsmeyer
|
|
gptkbp:domain
|
gptkb:BH1
gptkb:BH4
BH3
BH2
|
|
gptkbp:function
|
regulation of apoptosis
|
|
gptkbp:has_anti-apoptotic_members
|
gptkb:Bcl-2
gptkb:Bcl-xL
gptkb:Mcl-1
|
|
gptkbp:has_pro-apoptotic_members
|
gptkb:Puma
gptkb:Bid
gptkb:Bax
gptkb:Bcl-G
gptkb:Bcl-Rambo
gptkb:Bik
gptkb:Bim
gptkb:Bmf
gptkb:Noxa
gptkb:Bak
HRK
Bad
|
|
gptkbp:hasMember
|
gptkb:Bcl-2
gptkb:Bcl-xL
gptkb:Puma
gptkb:Bid
gptkb:Bax
gptkb:Bcl-B
gptkb:Bcl-G
gptkb:Bcl-Rambo
gptkb:Bcl-w
gptkb:Bcl2A1
gptkb:Bcl2L10
gptkb:Bcl2L13
gptkb:Bcl2L14
gptkb:Bcl2L15
gptkb:Bcl2L16
gptkb:Bcl2L17
gptkb:Bcl2L18
gptkb:Bcl2L19
gptkb:Bcl2L20
gptkb:Bcl2L21
gptkb:Bcl2L22
gptkb:Bcl2L23
gptkb:Bcl2L24
gptkb:Bcl2L25
gptkb:Bcl2L26
gptkb:Bcl2L30
gptkb:Bcl2L31
gptkb:Bcl2L32
gptkb:Bcl2L33
gptkb:Bcl2L34
gptkb:Bcl2L35
gptkb:Bcl2L37
gptkb:Bcl2L38
gptkb:Bcl2L39
gptkb:Bcl2L41
gptkb:Bcl2L42
gptkb:Bcl2L43
gptkb:Bcl2L44
gptkb:Bcl2L49
gptkb:Bcl2L51
gptkb:Bcl2L52
gptkb:Bcl2L53
gptkb:Bcl2L61
gptkb:Bcl2L62
gptkb:Bcl2L63
gptkb:Bcl2L65
gptkb:Bcl2L71
gptkb:Bcl2L72
gptkb:Bcl2L73
gptkb:Bcl2L75
gptkb:Bcl2L76
gptkb:Bcl2L77
gptkb:Bcl2L81
gptkb:Bcl2L83
gptkb:Bcl2L89
gptkb:Bcl2L91
gptkb:Bik
gptkb:Bim
gptkb:Bmf
gptkb:Mcl-1
gptkb:Noxa
gptkb:Bak
HRK
Bad
Bcl2L100
Bcl2L27
Bcl2L28
Bcl2L29
Bcl2L36
Bcl2L40
Bcl2L45
Bcl2L46
Bcl2L47
Bcl2L48
Bcl2L50
Bcl2L54
Bcl2L55
Bcl2L56
Bcl2L57
Bcl2L58
Bcl2L59
Bcl2L60
Bcl2L64
Bcl2L66
Bcl2L67
Bcl2L68
Bcl2L69
Bcl2L70
Bcl2L74
Bcl2L78
Bcl2L79
Bcl2L80
Bcl2L82
Bcl2L84
Bcl2L85
Bcl2L86
Bcl2L87
Bcl2L88
Bcl2L90
Bcl2L92
Bcl2L93
Bcl2L94
Bcl2L95
Bcl2L96
Bcl2L97
Bcl2L98
Bcl2L99
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
Bcl-2 protein family
|
|
gptkbp:inhibitedBy
|
apoptosis
|
|
gptkbp:location
|
gptkb:endoplasmic_reticulum
nuclear envelope
mitochondrial outer membrane
|
|
gptkbp:promotion
|
apoptosis
|
|
gptkbp:regulates
|
cell survival
cell death
caspase activation
cytochrome c release
mitochondrial outer membrane permeabilization
|
|
gptkbp:role
|
gptkb:cancer
neurodegenerative disease
autoimmune disease
|
|
gptkbp:bfsParent
|
gptkb:BAD_(Bcl-2-associated_death_promoter)
gptkb:BAD_protein
|
|
gptkbp:bfsLayer
|
6
|