interleukin-27

GPTKB entity

Statements (23)
Predicate Object
gptkbp:instanceOf gptkb:protein
cytokine
gptkbp:category immunology
cytokine
gptkbp:composedOf EBI3 subunit
IL27A subunit
gptkbp:discoveredIn 2002
gptkbp:encodedBy IL27 gene
gptkbp:foundIn humans
mice
gptkbp:function regulation of T cell activity
inhibition of Th17 cell development
promotion of Th1 cell differentiation
https://www.w3.org/2000/01/rdf-schema#label interleukin-27
gptkbp:inhibitedBy inflammatory cytokine production
gptkbp:producedBy activated antigen-presenting cells
gptkbp:promotion interferon-gamma production
gptkbp:receptorComponent gptkb:gp130
WSX-1
gptkbp:recipient interleukin-27 receptor
gptkbp:regulates immune response
gptkbp:bfsParent gptkb:interleukin-12
gptkbp:bfsLayer 8