BRCA1 Associated RING Domain 1
GPTKB entity
Statements (28)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:gene |
| gptkbp:alsoKnownAs |
gptkb:BARD1
|
| gptkbp:discoveredBy |
Wu LC et al.
|
| gptkbp:discoveredIn |
1996
|
| gptkbp:domain |
gptkb:BRCT_domain
RING finger domain |
| gptkbp:encodedBy |
BARD1 gene
|
| gptkbp:Entrez_Gene_ID |
gptkb:ENSG00000138376
580 |
| gptkbp:expressedIn |
various tissues
|
| gptkbp:formsComplexWith |
gptkb:BRCA1
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
DNA repair
tumor suppression E3 ubiquitin-protein ligase activity |
| gptkbp:interactsWith |
gptkb:BRCA1
|
| gptkbp:location |
chromosome 2q34-q35
|
| gptkbp:mutationAssociatedWith |
gptkb:cancer
|
| gptkbp:OMIM |
601593
|
| gptkbp:orthologIn |
gptkb:Danio_rerio
gptkb:Mus_musculus |
| gptkbp:regulates |
apoptosis
cell cycle |
| gptkbp:UniProtID |
gptkb:Q99728
|
| gptkbp:bfsParent |
gptkb:BARD1
|
| gptkbp:bfsLayer |
8
|
| https://www.w3.org/2000/01/rdf-schema#label |
BRCA1 Associated RING Domain 1
|