BRCA1-BRCA2-containing complex (BRCC)

GPTKB entity

Statements (22)
Predicate Object
gptkbp:instanceOf gptkb:protein
gptkbp:associatedWith gptkb:cancer
gptkbp:biologicalProcess DNA binding
E3 ubiquitin ligase activity
gptkbp:discoveredIn 1990s
gptkbp:function DNA repair
homologous recombination
gptkbp:hasProtein gptkb:BARD1
gptkb:PALB2
gptkb:BRCA1
gptkb:BRCA2
gptkb:RAD51
https://www.w3.org/2000/01/rdf-schema#label BRCA1-BRCA2-containing complex (BRCC)
gptkbp:location gptkb:nucleus
gptkbp:regulates cell cycle checkpoint
DNA double-strand break repair
gptkbp:subunit gptkb:BRCC36
BRCC45
MERIT40
RAP80
gptkbp:bfsParent gptkb:BRCC1
gptkbp:bfsLayer 7