Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:alternativeName |
gptkb:Bcl-2
B-cell lymphoma 2 protein |
| gptkbp:associatedWith |
chronic lymphocytic leukemia
various cancers follicular lymphoma |
| gptkbp:discoveredBy |
gptkb:John_C._Reed
|
| gptkbp:discoveredIn |
1984
|
| gptkbp:encodedBy |
gptkb:BCL2_gene
|
| gptkbp:family |
gptkb:Bcl-2_family
|
| gptkbp:foundIn |
gptkb:Homo_sapiens
|
| gptkbp:function |
regulation of apoptosis
inhibition of cell death |
| https://www.w3.org/2000/01/rdf-schema#label |
BCL2 protein
|
| gptkbp:interactsWith |
gptkb:BAD_protein
BAX protein BCL2L1 protein BCL2L11 protein |
| gptkbp:locatedOnChromosome |
chromosome 18q21.33
|
| gptkbp:location |
gptkb:endoplasmic_reticulum
nuclear envelope mitochondrial outer membrane |
| gptkbp:molecularWeight |
26 kDa
|
| gptkbp:PDB |
gptkb:1G5M
|
| gptkbp:structure |
contains BH1, BH2, BH3, BH4 domains
|
| gptkbp:UniProtID |
P10415
|
| gptkbp:bfsParent |
gptkb:BAD_gene
gptkb:RAF1_protein gptkb:BECN1_gene |
| gptkbp:bfsLayer |
7
|