Statements (30)
Predicate | Object |
---|---|
gptkbp:instanceOf |
gptkb:gene
|
gptkbp:alias |
gptkb:v-raf_murine_sarcoma_viral_oncogene_homolog_B1
gptkb:BRAF gptkb:proto-oncogene_B-Raf |
gptkbp:associatedWith |
gptkb:cancer
colorectal cancer melanoma |
gptkbp:discoveredBy |
gptkb:Mariano_Barbacid
|
gptkbp:encodes |
gptkb:B-Raf_protein
|
gptkbp:Entrez_Gene_ID |
673
|
gptkbp:expressedIn |
human tissues
|
gptkbp:function |
serine/threonine-protein kinase activity
|
gptkbp:HGNC_ID |
1097
|
https://www.w3.org/2000/01/rdf-schema#label |
B-raf proto-oncogene
|
gptkbp:involvedIn |
gptkb:MAPK/ERK_signaling_pathway
|
gptkbp:locatedOnChromosome |
gptkb:7q34
|
gptkbp:mutationAssociatedWith |
V600E
|
gptkbp:OMIM |
164757
|
gptkbp:orthologIn |
gptkb:mouse
gptkb:zebrafish right |
gptkbp:regulates |
cell differentiation
cell survival cell growth |
gptkbp:target |
gptkb:encorafenib
gptkb:dabrafenib gptkb:vemurafenib |
gptkbp:UniProtID |
gptkb:P15056
|
gptkbp:bfsParent |
gptkb:BRAF
|
gptkbp:bfsLayer |
5
|