Statements (30)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:gene
|
| gptkbp:alias |
gptkb:v-raf_murine_sarcoma_viral_oncogene_homolog_B1
gptkb:BRAF gptkb:proto-oncogene_B-Raf |
| gptkbp:associatedWith |
gptkb:cancer
gptkb:melanoma colorectal cancer |
| gptkbp:discoveredBy |
gptkb:Mariano_Barbacid
|
| gptkbp:encodes |
gptkb:B-Raf_protein
|
| gptkbp:Entrez_Gene_ID |
673
|
| gptkbp:expressedIn |
human tissues
|
| gptkbp:function |
serine/threonine-protein kinase activity
|
| gptkbp:HGNC_ID |
1097
|
| gptkbp:involvedIn |
gptkb:MAPK/ERK_signaling_pathway
|
| gptkbp:locatedOnChromosome |
gptkb:7q34
|
| gptkbp:mutationAssociatedWith |
V600E
|
| gptkbp:OMIM |
164757
|
| gptkbp:orthologIn |
gptkb:mouse
gptkb:right gptkb:zebrafish |
| gptkbp:regulates |
cell differentiation
cell survival cell growth |
| gptkbp:target |
gptkb:encorafenib
gptkb:dabrafenib gptkb:vemurafenib |
| gptkbp:UniProtID |
gptkb:P15056
|
| gptkbp:bfsParent |
gptkb:BRAF
|
| gptkbp:bfsLayer |
6
|
| https://www.w3.org/2000/01/rdf-schema#label |
B-raf proto-oncogene
|