Statements (23)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
|
| gptkbp:activatedBy |
proteolytic cleavage
|
| gptkbp:alsoKnownAs |
gptkb:Caspase-3
|
| gptkbp:discoveredBy |
1996
|
| gptkbp:EC_number |
3.4.22.56
|
| gptkbp:enzymeClassification |
peptidase
|
| gptkbp:function |
cysteine-aspartic acid protease
execution-phase apoptosis protease |
| gptkbp:gene |
gptkb:CASP3
|
| https://www.w3.org/2000/01/rdf-schema#label |
Apopain
|
| gptkbp:inhibitedBy |
inhibitor of apoptosis proteins (IAPs)
|
| gptkbp:locatedOnChromosome |
chromosome 4q34
|
| gptkbp:molecularWeight |
32 kDa
|
| gptkbp:organism |
gptkb:Homo_sapiens
|
| gptkbp:PDB |
gptkb:1PAU
|
| gptkbp:role |
gptkb:Alzheimer's_disease
gptkb:cancer neurodegenerative diseases |
| gptkbp:structure |
heterotetramer (two large and two small subunits)
|
| gptkbp:substrate |
DEVD peptide sequence
|
| gptkbp:UniProtID |
P42574
|
| gptkbp:bfsParent |
gptkb:P49918
|
| gptkbp:bfsLayer |
7
|