Properties (64)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gene
|
| gptkbp:associatedWith |
ataxia-telangiectasia
|
| gptkbp:code |
gptkb:ATM_protein
|
| gptkbp:diedIn |
cell cycle regulation
|
| gptkbp:geneticDiversity |
ataxia-telangiectasia syndrome
|
| gptkbp:hasRole |
immune response
|
| https://www.w3.org/2000/01/rdf-schema#label |
ATM gene
|
| gptkbp:interactsWith |
p53 protein
|
| gptkbp:involvedIn |
DNA damage response
|
| gptkbp:isAssociatedWith |
diabetes
autoimmune diseases chronic diseases metabolic syndrome lung cancer breast cancer lymphoma gastrointestinal cancers hypersensitivity to ionizing radiation |
| gptkbp:isDistributedBy |
chromosomal_rearrangements
|
| gptkbp:isInvolvedIn |
apoptosis
cellular homeostasis cellular metabolism cellular stress response metabolic processes neuroinflammation cellular senescence tumor suppression cellular aging cellular differentiation genomic stability neurodegeneration cellular signaling cellular repair mechanisms cellular repair pathways |
| gptkbp:isLinkedTo |
age-related diseases
neurodegenerative diseases increased cancer risk prostate cancer cardiovascular diseases chronic inflammation skin cancer neurodevelopmental disorders endocrine disorders |
| gptkbp:isLocatedIn |
various tissues
embryonic development brain tissue immune cells |
| gptkbp:isPartOf |
tumor microenvironment
cellular signaling pathways DNA damage checkpoint. DNA repair pathway PI3K-like kinase family cancer progression pathways |
| gptkbp:isRegulatedBy |
transcription factors
|
| gptkbp:isStudiedIn |
personalized medicine
therapeutic interventions cancer research therapeutic targets biomarker_development |
| gptkbp:isTrainedIn |
gene therapy
|
| gptkbp:isUtilizedFor |
double-strand break repair
|
| gptkbp:locatedIn |
human chromosome 11q22.3
|
| gptkbp:notableFeature |
many species
|
| gptkbp:regulates |
cellular response to stress
|