Statements (39)
| Predicate | Object |
|---|---|
| gptkbp:instanceOf |
gptkb:protein
gptkb:G_protein-coupled_receptor |
| gptkbp:alternativeName |
AGTR1
AT1R Angiotensin II type 1 receptor |
| gptkbp:binds |
gptkb:angiotensin_II
|
| gptkbp:discoveredIn |
1990s
|
| gptkbp:encodedBy |
gptkb:AGTR1_gene
|
| gptkbp:enemyOf |
gptkb:valsartan
gptkb:telmisartan gptkb:olmesartan gptkb:irbesartan gptkb:losartan azilsartan candesartan eprosartan |
| gptkbp:expressedIn |
gptkb:cancer
gptkb:adrenal_gland gptkb:kidney brain heart blood vessels |
| gptkbp:function |
regulation of blood pressure
regulation of fluid balance |
| gptkbp:HGNC_ID |
333
|
| https://www.w3.org/2000/01/rdf-schema#label |
AT1 receptor
|
| gptkbp:locatedIn |
gptkb:cell_membrane
|
| gptkbp:medium |
cell proliferation
inflammation vasoconstriction aldosterone secretion |
| gptkbp:relatedTo |
heart failure
hypertension chronic kidney disease |
| gptkbp:subspecies |
AT1A receptor
AT1B receptor |
| gptkbp:UniProtID |
P30556
|
| gptkbp:bfsParent |
gptkb:angiotensin_receptor
|
| gptkbp:bfsLayer |
6
|