|
gptkbp:instanceOf
|
angiotensin II receptor blocker
antihypertensive drug
|
|
gptkbp:approvalYear
|
2002
|
|
gptkbp:approvedBy
|
gptkb:FDA
|
|
gptkbp:ATCCode
|
gptkb:C09CA08
|
|
gptkbp:bioavailability
|
26%
|
|
gptkbp:brand
|
gptkb:Benicar
gptkb:Olmetec
gptkb:Votum
|
|
gptkbp:CASNumber
|
gptkb:144689-63-4
|
|
gptkbp:category
|
prodrug
imidazole
biphenyl compound
tetrazole
|
|
gptkbp:cause
|
sprue-like enteropathy
|
|
gptkbp:chemicalFormula
|
C24H26N6O3
|
|
gptkbp:contraindication
|
pregnancy
bilateral renal artery stenosis
|
|
gptkbp:discoveredBy
|
gptkb:Daiichi_Sankyo
|
|
gptkbp:eliminationHalfLife
|
13 hours
|
|
gptkbp:excretion
|
urine
feces
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
olmesartan
|
|
gptkbp:interactsWith
|
gptkb:NSAIDs
gptkb:aliskiren
lithium
potassium-sparing diuretics
|
|
gptkbp:KEGGID
|
D08227
|
|
gptkbp:legalStatus
|
prescription only
|
|
gptkbp:mechanismOfAction
|
blocks angiotensin II type 1 receptor
|
|
gptkbp:MedlinePlusID
|
a603006
|
|
gptkbp:metabolism
|
liver
|
|
gptkbp:molecularWeight
|
446.50 g/mol
|
|
gptkbp:pregnancyCategory
|
D (US)
|
|
gptkbp:proteinBinding
|
99%
|
|
gptkbp:PubChem_CID
|
gptkb:CHEMBL1201197
gptkb:DB00275
135409568
|
|
gptkbp:routeOfAdministration
|
oral
|
|
gptkbp:sideEffect
|
diarrhea
dizziness
fatigue
headache
|
|
gptkbp:synonym
|
gptkb:olmesartan_medoxomil
|
|
gptkbp:UNII
|
0Y2S3XUQ5H
|
|
gptkbp:usedFor
|
hypertension
|
|
gptkbp:bfsParent
|
gptkb:Azor
|
|
gptkbp:bfsLayer
|
6
|