|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:AT1
AT1R
angiotensin II receptor, type 1
|
|
gptkbp:associatedWith
|
gptkb:cardiovascular_disease
hypertension
|
|
gptkbp:discoveredBy
|
1991
|
|
gptkbp:encodes
|
angiotensin II receptor type 1 protein
|
|
gptkbp:Entrez_Gene_ID
|
185
ENSG00000144891
|
|
gptkbp:expressedIn
|
gptkb:adrenal_gland
gptkb:kidney
heart
vascular smooth muscle
|
|
gptkbp:fullName
|
angiotensin II receptor type 1
|
|
gptkbp:function
|
regulates blood pressure
regulates electrolyte balance
mediates effects of angiotensin II
|
|
gptkbp:hasTranscriptVariant
|
multiple
|
|
gptkbp:HGNC_ID
|
333
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
AGTR1 gene
|
|
gptkbp:locatedOnChromosome
|
3q24
|
|
gptkbp:mutationAssociatedWith
|
can cause altered blood pressure regulation
|
|
gptkbp:OMIM
|
106165
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
gptkb:lion
gptkb:mouse
right
|
|
gptkbp:proteinFamily
|
gptkb:G_protein-coupled_receptor
|
|
gptkbp:target
|
gptkb:angiotensin_receptor_blockers
|
|
gptkbp:UniProtID
|
P30556
|
|
gptkbp:bfsParent
|
gptkb:angiotensin_receptor
|
|
gptkbp:bfsLayer
|
6
|