|
gptkbp:instanceOf
|
gptkb:gene
|
|
gptkbp:alternativeName
|
gptkb:HIF-1β
gptkb:Dioxin_receptor_nuclear_translocator
bHLHe76
|
|
gptkbp:associatedWith
|
gptkb:Type_2_diabetes
|
|
gptkbp:biologicalProcess
|
transcription regulation
DNA binding
response to hypoxia
protein dimerization activity
response to xenobiotic stimulus
|
|
gptkbp:chromosomeArm
|
q
|
|
gptkbp:discoveredBy
|
1993
|
|
gptkbp:encodes
|
Aryl hydrocarbon receptor nuclear translocator protein
|
|
gptkbp:Entrez_Gene_ID
|
gptkb:ENSG00000143437
405
|
|
gptkbp:expressedIn
|
many tissues
|
|
gptkbp:fullName
|
gptkb:Aryl_hydrocarbon_receptor_nuclear_translocator
|
|
gptkbp:function
|
transcription factor
dimerizes with AHR
dimerizes with HIF1A
involved in hypoxia response
regulates xenobiotic metabolism
|
|
gptkbp:geneType
|
protein-coding
|
|
gptkbp:hasTranscriptVariant
|
multiple
|
|
gptkbp:HGNC_ID
|
701
|
|
https://www.w3.org/2000/01/rdf-schema#label
|
ARNT gene
|
|
gptkbp:interactsWith
|
gptkb:SIM1
gptkb:SIM2
gptkb:AHR
gptkb:EPAS1
gptkb:NPAS4
gptkb:HIF1A
gptkb:CLOCK
|
|
gptkbp:length_(genomic)
|
~67 kb
|
|
gptkbp:locatedOnChromosome
|
1
q21
|
|
gptkbp:location_(GRCh38)
|
1q21.3
|
|
gptkbp:numberOfExons
|
22
|
|
gptkbp:OMIM
|
601074
|
|
gptkbp:organism
|
gptkb:Homo_sapiens
|
|
gptkbp:orthologIn
|
mouse Arnt
rat Arnt
|
|
gptkbp:pathway
|
gptkb:Aryl_hydrocarbon_receptor_pathway
gptkb:Hypoxia-inducible_factor_pathway
|
|
gptkbp:proteinFamily
|
bHLH-PAS family
|
|
gptkbp:subcellularLocation
|
gptkb:nucleus
|
|
gptkbp:UniProtID
|
gptkb:P27540
|
|
gptkbp:bfsParent
|
gptkb:ARNT
gptkb:HIF-1β
|
|
gptkbp:bfsLayer
|
7
|